Grignard Reaction

The Grignard Reaction Synthesis of triphenylmethanol Josh Wilson Chem 443-003 January 1,2012-February 7,2012 Introduction In this test we synthesized triphenylmethanol from a Grignard reagent and an ester. To form triphenylmethanol we reacted methyl benzoate with phenylmagnesium bromide. Reaction Scheme: system An organo golden compound is an original compound that contains a ampere-second-metallic bond. The metal can be Li, Na, Mg, Cu, Pd or any other transitional metal. In this testing groundoratory we used Mg as our metallic portion of the organometallic compound. Organometallic compounds be special in that they cause Carbon to become a nucleophile. More specifically in this lab we used R-Mg-Br an alkyl magnesium halide to project the nucleophillic properties onto the Carbon atom, cognise as a Grignard reagent because of it founder chemist Victor Grignard. The innovation of Grignard reactions is to create a C-C bond, more specifically a 3rd or a secondary alcohol. The Grignard reagents ar usually created with the solvents anhydrous diethyl ethoxyethane or THF and are very air sensitive. The Grignard reagent are very prefatory which make them very good proton acceptors. In our experiment we created a tertiary alcohol by exploitation an ester and carbonyl molecule.

The ester is born-again to a ketone than immediately reacts with the Grignard reagent to give the tertiary alcohol, triphenylmethanol. Reaction machine Procedure A. Preparation of the Grignard reagent * Weigh some .5 g of Magnesium turnings * engage mortar and pastel to fret turnings * ! Put tunings into around layabout flaskful * Assemble implement * Prepare 2.4 mL of bromobenzene in 5 mL of anhydrous diethyl ether * Swirl mixture, than add 5mL to round bottom flask * Reflux reaction * Add .5 mL increments of the impractical reply over 10 minutes B. Synthesis of Triphenylmethanol * Dissolve 1.2 mL of methyl benzoate in 5 mL of anhydrous diethyl ether *...If you call for to get a full essay, order it on our website: BestEssayCheap.com

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